Xeomin in Seoul (Hongdae): Purified Botulinum Toxin for Wrinkles
Xeomin is a purified botulinum toxin type A (incobotulinumtoxinA) that relaxes muscles to soften frown lines, forehead lines and crow's feet, and can slim the jaw. It contains no accessory proteins, which may lower the chance of antibody resistance. Results usually appear in 3 to 5 days and last 3 to 4 months.
✦ Medically reviewed by the KLEAM Medical Team · Last updated:
Key facts at a glance
- Treatment time
- 10–15 min
- Comfort
- Fine needle; numbing cream or ice if needed
- Downtime
- None; avoid exercise and massage for 24 hours
- Results visible
- 3–5 days; peak at about 2 weeks
- How long it lasts
- About 3–4 months
- Recommended sessions
- 1, repeated for maintenance
Who it suits
- Frown lines between the brows
- Forehead lines and crow's feet
- Jaw slimming (masseter) and teeth clenching
- Regular toxin users concerned about resistance
- People wanting a refreshed look with no downtime
Please consult us first if
- Pregnant or breastfeeding
- Neuromuscular disorders such as myasthenia gravis
- Infection at the injection site
- Allergy to botulinum toxin products
How it works
Xeomin blocks the nerve signals that tell targeted muscles to contract. When those muscles relax, the skin over them creases less, so dynamic wrinkles soften. In larger muscles such as the masseter, regular treatment can slim the lower face.
What sets Xeomin apart is its manufacturing: complexing proteins are removed, leaving only the active toxin. This 'naked' formulation is thought to reduce the risk of the body forming neutralizing antibodies over years of treatment. Xeomin is FDA-approved for glabellar (frown) lines.
Injections take a few minutes with a very fine needle. Most people feel quick pinches only.
How it compares
| Compared with | Difference |
|---|---|
| Botox (onabotulinumtoxinA) | Both relax muscles with similar timing and duration; Xeomin has no complexing proteins, which may matter for long-term users. |
| Korean toxins | Korean-made toxins are often more budget-friendly, while Xeomin is chosen for its purified formulation. |
Your visit, step by step
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Message us on WhatsApp or KakaoTalk
Send your preferred date, time and any photos or questions about Xeomin. Our English-speaking team replies with availability and what to expect. You can also call +82-10-7368-4441.
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Arrive at Hongik Univ. Station Exit 1
KLEAM Clinic Hongdae is on the 3rd floor of L7 Hongdae by LOTTE, 141 Yanghwa-ro, right by Exit 1 (Line 2, AREX Airport Railroad and Gyeongui-Jungang Line). Please arrive about 10 minutes early with your passport.
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Consultation in English
A doctor reviews your skin, medical history, medications and travel dates, explains whether Xeomin suits you, and agrees a plan and quote before anything is done. Japanese-friendly support is also available.
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Treatment
Your Xeomin session is performed in a private treatment room. Comfort measures such as numbing cream or cooling are used where appropriate, and you can ask questions at any point.
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Aftercare and flight tips
You leave with written aftercare in English. Stay upright for about 4 hours and avoid rubbing the area. You can fly the same or next day. Message us on WhatsApp if anything concerns you after you fly home.
Aftercare & travel tips
- Stay upright for about 4 hours after treatment
- Do not rub or massage treated areas for 24 hours
- Avoid strenuous exercise, saunas and alcohol for 24 hours
- Makeup can usually be applied the next day
- Flying is fine the same or next day
- Small bumps or redness typically fade within an hour
Frequently asked questions
How much does Xeomin cost in Seoul?
Cost depends on the area and number of units needed, for example frown lines versus jaw slimming. Message us on WhatsApp with the areas you want treated, and the doctor confirms an exact quote at consultation before treatment. Because every face and skin type is different, the doctor confirms what is suitable for you during your consultation, and results vary from person to person.
Is Xeomin better than Botox?
Not necessarily better, but different. Both work similarly and last about 3 to 4 months. Xeomin is purified of accessory proteins, so some doctors prefer it for people who have used toxin for years or feel it has become less effective.
How soon will I see results?
Most people notice softening within 3 to 5 days, with peak effect at about 2 weeks. If you are traveling, treat early in your trip so the doctor can check results before you leave if needed. If you are visiting Seoul for a short time, tell us your travel dates when you book so the doctor can plan treatment timing around your flight.
Can I fly after Xeomin?
Yes. Flying the same or next day is generally fine. Try not to rub your face or press on treated areas, for example with a tight sleep mask, for the first 24 hours. Our English-speaking team can answer follow-up questions on WhatsApp or KakaoTalk before your visit and after you return home.
Does it hurt?
Xeomin uses a very fine needle, and most people feel only brief pinches. The whole procedure takes 10 to 15 minutes. Numbing cream or ice is available for sensitive patients. The doctor will also review your medical history, current medications and any previous treatments before recommending anything.
Is Xeomin safe?
Xeomin is FDA-approved and widely used. Temporary side effects can include small bruises, mild headache or, rarely, a slightly heavy brow or eyelid that resolves as the effect wears off. A doctor reviews your health history before treatment. Written aftercare instructions in English are provided, and you can message us any time if something does not feel right.
Last updated: 2026-10-01. This page is for general information and is not a diagnosis. Suitability, dosage and results vary by person and are decided with a doctor at your consultation.
Why international patients choose KLEAM
Visit us
KLEAM Clinic Hongdae
3F, L7 Hongdae by LOTTE, 141 Yanghwa-ro, Mapo-gu, Seoul
Right by Hongik Univ. Station Exit 1 (Line 2 · AREX · Gyeongui-Jungang)
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+82-10-7368-4441
Weekdays 10:30–20:30 · Weekends 10:30–17:00 · No lunch break
Explore popular treatments
Xeomin in Hongdae – Smooth Wrinkles with a Purified Touch
Looking for a natural, clinically refined way to soften facial lines—without additives? Xeomin® is a next-generation wrinkle treatment that offers the same muscle-relaxing effects as Botox®, but with a uniquely purified formula. At our clinic in Hongdae, we provide safe, effective Xeomin treatments tailored to your personal cosmetic or medical needs.
What is Xeomin?
Xeomin® (incobotulinumtoxinA) is a purified form of botulinum toxin type A used to temporarily relax overactive muscles that cause dynamic wrinkles and muscle tension. Unlike Botox or Dysport, Xeomin is manufactured without any accessory proteins—making it a “naked” neurotoxin. This can reduce the risk of resistance or allergic reactions in long-term use.
Xeomin is commonly used to improve:
- Frown lines (glabellar lines)
- Crow’s feet (smile lines around the eyes)
- Forehead creases
- Bunny lines (nose wrinkles)
- Chin dimpling
- Neck bands
- Gummy smile
- Jaw slimming (masseter treatment)
It can also be used to subtly lift the brow or soften a tense jawline.
Why Choose Xeomin?
Key Benefits:
✅ Additive-free formulation – no unnecessary proteins
✅ Reduced risk of antibody resistance over time
✅ Quick procedure (about 10–15 minutes)
✅ No downtime – resume normal activities immediately
✅ Visible effects within 3–5 days
✅ Results that last 3 to 4 months
✅ Suitable for patients who’ve built resistance to other botulinum products
Xeomin offers a more targeted approach to wrinkle reduction—perfect for patients seeking a minimalist, high-purity option.
Medical Applications of Xeomin
Beyond aesthetics, Xeomin is approved and widely used for therapeutic purposes such as:
- Chronic migraines – Helps reduce frequency and severity
- Hyperhidrosis (excessive sweating) – Commonly used on underarms, hands, and feet
- Bruxism (teeth grinding) – Relieves jaw tension and facial pain
- Cervical dystonia – Treats involuntary neck spasms
- Blepharospasm – Controls uncontrolled eyelid twitching
- Facial asymmetry post-stroke or Bell’s palsy – Helps balance facial muscle activity
What to Expect During Treatment
Xeomin is injected with a very fine needle into specific facial muscles. Treatment typically takes 10 to 15 minutes, with minimal discomfort. Most patients don’t require numbing, though topical anesthetic is available upon request.
Post-treatment, you can return to daily activities right away, but avoid heavy exercise or facial massages for 24 hours to ensure optimal results.
Who is a Good Candidate?
You may be a great candidate for Xeomin if:
- You are 18–65 years old
- You want a cleaner alternative to traditional Botox
- You’ve developed resistance or allergic reactions to Botox/Dysport
- You seek non-surgical treatment for wrinkles or muscle-related issues
- You’re not pregnant, breastfeeding, or diagnosed with certain neurological conditions
Consultation is essential to confirm Xeomin is right for you.
How Long Do Results Last?
You’ll begin noticing results within 3 to 5 days, with peak effects around 2 weeks. Xeomin results typically last 3 to 4 months, and regular sessions are encouraged to maintain a smooth, natural appearance.
Book Your Xeomin Appointment in Hongdae
At our cutting-edge clinic in Hongdae, we offer expert Xeomin treatments in a clean, comfortable environment. Whether you’re new to wrinkle relaxers or looking for a purified alternative, our experienced injectors provide custom treatment plans tailored to your goals—cosmetic or medical.
